Jinchuan Xing

xing jin vert 500wAssistant Professor, Genetics

Jinchuan Xing joined Department of Genetics as an Assistant Professor at Rutgers in 2012. Dr. Xing is a human/primate geneticist and received his Ph.D. from Louisiana State University in 2005. After spending an additional year at LSU as a postdoctoral fellow, Dr. Xing moved to University of Utah as a postdoctoral fellow and studied human population genetics and natural selection until 2011.

The long-term research interest of his laboratory is to understand the mechanisms and consequences of human genomic variation, with focuses on mobile DNA elements, evolutionary genetics, and human disease. They will combine computational and experimental tools to perform genome-wide analyses. His previous projects involve elucidating human population history and genetic adaptation at both global and regional scale, with or without disease implication.

Dr. Xing's current projects include studying genetic/phenotypic adaptation in a Mongolian population living on the Qinghai-Tibetan plateau, and investigating the human evolutionary history in South Asia.

Mobile element biology

Human demographic history and population diversity

Disease-causing genes identification using genome-wide data

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Xing, J.*, T. Wuren*, T. S. Simonson*, W. S. Watkins, D. J. Witherspoon, W. Wu, G. Qin, C. D. Huff, L. B. Jorde, and R. L. Ge (2013) Genomic analysis of nature selection and phenotypic variation in high-altitude Mongolians. PLOS Genetics

Xing, J., D. J. Witherspoon, and L. B. Jorde (2013) Mobile element biology – new possibilities with high-throughput sequencing. Trends in Genetics 29(5):280–289

The 1000 Genomes Project Consortium (2012) An integrated map of genetic variation from 1,092 human genomes. Nature 491:56–65

Xing, J., W. S. Watkins, Y. Hu, C. D. Huff, A. Sabo, D. M. Muzny, M. J. Bamshad, R. A. Gibbs, L. B. Jorde, and F. Yu (2010) Inference of human expansion in Eurasia and genetic diversity in India. Genome Biology 11:R113

The 1000 Genomes Project Consortium (2010) A map of human genome variation from population scale sequencing. Nature 467:1061-1073

Xing, J., W. S. Watkins, A. Shlien, E. Walker, C. D. Huff, D. J. Witherspoon, Y. Zhang, T. S. Simonson, R. B. Weiss, J. D. Schiffman, D. Malkin, S. R. Woodward and L. B. Jorde (2010) Toward a more Uniform Sampling of Human Genetic Diversity: A Survey of Worldwide Populations by High-density Genotyping. Genomics 96:199–210

Simonson, T. S., Y. Yang, C. D. Huff, H. Yun, G. Qin, D. J. Witherspoon, Z. Bai, F. R. Lorenzo, J. Xing, L. B. Jorde, J. T. Prchal, and R. Ge (2010) Genetic Evidence for High-Altitude Adaptation in Tibet. Science 329 (5987):72-5

Xing, J., Y. Zhang, K. Han, A. H. Salem, S. K. Sen, C. D. Huff, Q. Zhou, E. F. Kirkness, S. Levy, M.A. Batzer, and L. B. Jorde (2009) Mobile elements create structural variation: analysis of a complete human genome. Genome Research 19(9):1516-26

Xing, J., W. S. Watkins, D. J. Witherspoon, Y. Zhang, S. L. Guthery, R. Thara, B. J. Mowry, K. Bulayeva, R. B. Weiss, and L. B. Jorde (2009) Fine-Scaled Human Genetic Structure Revealed by SNP Microarrays. Genome Research 19(5):815-25

Xing, J., W. S. Watkins, Y. Zhang, D. J. Witherspoon, and L. B. Jorde (2008) High Fidelity of Whole-Genome Amplified DNA on High-Density Single Nucleotide Polymorphism Arrays. Genomics 92(6):452-6

Xing, J., D. J. Witherspoon, W. S. Watkins, Y. Zhang, W. Tolpinrud and L. B. Jorde. (2008) HapMap tagSNP transferability in multiple populations: general guidelines. Genomics 92:41-51

Xing, J., D. J. Witherspoon, D. A. Ray, M. A. Batzer and L. B. Jorde (2007) Mobile elements and primate evolution. American Journal of Physical Anthropology Suppl 45: 2-19

Xing, J., H. Wang, Y. Zhang, D. A. Ray, A. J. Tosi, T. R. Disotell and M. A. Batzer (2007) A mobile element based evolutionary history of guenons (Tribe Cercopithecini). BMC Biology 5:5

Xing, J.*, H. Wang*, V. P. Belancio, R. Cordaux, P. L. Deininger and M. A. Batzer (2006) Emergence of new primate genes by retrotransposon-mediated sequence transduction. Proceedings of the National Academy of Sciences, USA 103: 17608-17613